The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Open, uncontrolled studies suggest clozapine can have mood–stabilizing effects in treatment–resistant bipolar disorder. Unfortunately, the side effect profile limits clozapine’s use at high doses. We report a series of nine bipolar I disorder patients who improved on relatively low doses of clozapine add–on therapy (250 mg or lower). Retrospectively abstracted clinical data identified nine patients...