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AbstractAims/Hypothesis. To examine the prevalence of subclinical islet autoimmunity in children from two countries with a twofold to threefold difference in incidence of childhood Type I (insulin-dependent) diabetes mellitus.Methods. Sera were collected from 2860 English and 3053 Lithuanian non-diabetic schoolchildren according to the same protocol. Occult diabetes was excluded by blood glucose measurement...
Aims/hypothesis. The role of infections in the aetiology of Type I diabetes is controversial. Certain enteroviral infections might be involved in triggering the beta-cell destruction but insufficient exposure to early infections might increase the risk. We studied how the number of infections experienced during several periods from birth to onset influence diabetes risk.Methods. The study group came...
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