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Purpose: This prospective study evaluates the diagnostic potential of Cytokeratin 20 (CK 20) RT-PCR for the detection of disseminated tumor cells in bone marrow and blood of a large cohort of patients with ductal adenocarcinoma of the pancreas and the prognostic value on overall survival prediction. Methods: Between 1994 and 2003, 172 patients (83 male, 89 female; 13–82 years) with pancreatic ductal...