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One of the most crucial aspects of abdominal aortic aneurysm (AAA) diagnosis lies in the early detection of the aneurysm and its propensity for rupture. This study aims at determining whether the estimation of the aortic wall stiffness of the natural mechanical, pulsating motion of the aorta is feasible using high-resolution and high-frame-rate imaging in a murine model. Twelve wild-type (WT) mice...
The heart is a mechanical pump that is electrically driven. We have previously shown that the contractility of the cardiac muscle can reliably be used in order to assess the extent of ischemia. In this paper, in vivo imaging (35 MHz) was performed on anesthetized mice before and after left anterior descending (LAD) coronary artery ligation at high frame rates (Vevo 770, Visualsonics, Inc.) in order...
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