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Nanofluidic crystal (NFC) is attracting research interest as a novel nanofluidic material due to its various advantages over traditional microfabricated nanochannels. Crystal defects form during the self-assembly of NFC. In this work, we investigated the effects of crystal defects on the electrokinetics of NFC in the domain of micrometers (1–100 µm). We found that conductance of NFCs self-assembled...
This paper focuses on fabrication of opal structures by self-assembling silica spheres, which can be used as an array of high throughput and low cost reactors or micro-filters. The reactors can carry out hundreds different reactions in parallel; while there is about 50 nano-liter reagent consumed in each reactor. It not only provides large surface area for reaction, but also solves the issue of high...
Real-time physiological properties' characterization of living cells is important for bio-engineering applications such as drug screening. In this paper, we propose an integrated platform to automatically characterize muscle cell mechanics under a variety of culture conditions and drug stimuli in parallel. A Post-CMOS process is developed to fabricate the integrated chip, and then living muscle cells...
A promising combination of the semiconductor integrated system-on-a-chip (SoC) with the lab-on-a-chip (LOC) is brought in this paper. In this paper, we propose a new technology which enables monolithic integration of the self-assembled biological system, the MEMS structure, the microfluidic system, and CMOS electronic circuits together. Utilizing this approach, more functionality is introduced into...
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