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The sensitivity of flow crossmatch in detecting the presence and strength of DSA is largely influenced by HLA expression on donor lymphocytes. In this study, we characterized the extent of variability of HLA expression in different donor types and lymphocyte sources, as well as the factors that associated with the expression level.HLA expression was examined in a total of 516 crossmatches using pronased...
Many common and well-documented (CWD) alleles have not been assigned official World Health Organization (WHO) approved serologic equivalents, which often makes the reporting of time-sensitive deceased donor typing and virtual crossmatch very challenging. Here we report the characterization of the serologic reactivity of a relatively rare CWD allele, DRB1∗11:17.A 31year-old African American female...
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