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A human / mouse heterohybridoma obtained by fusion of a B-lymphocyte from a patient with chronic thrombozytopenia with the mouse myeloma cell line P3X63Ag8, was selected as a potential protein producer cell line for its stability, preferable growth characteristics, and endogenous production capacity. The cell line secretes an IgM antibody at titers between 30 and 100µg/ml. We have characterized...
The effect of various mistletoe preparations on cancer cells are well known [1]. We compared the induced cytotoxicity of ash and apple mistletoe extracts with common cytostatics such as Cisplatin, Paclita-xel and Doxorubicin. The effectiveness of these cancer therapeutics were depending on the concentration of the active agent, the cancer cell line and the presence of fetal calf serum (FCS) or mistletoe...
The seed coat is the first host or non-host tissue contacted by bruchids, suggesting its participation in the evolutionary adaptation of bruchids to favor legume seeds. In the present work, we studied the influence of seed coat on the ability of Callosobruchus maculatus (Coleoptera: Bruchidae F.) larvae to penetrate, develop in and survive on seeds. Our results showed that the oviposition, larval...
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