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Methods. In five monkeys, ONH tissue blood velocity (NBONH), determined using the laser speckle method, and intraocular pressure (IOP), blood pressure (BP), and pulse rate (PR) were measured 2h after a single unilateral instillation and after a 7-day twice-daily unilateral instillation of phenylephrine. In 20 aged patients (mean age: 70.4 years), the CRA circulation indices were determined by color...
Purpose The aim of this study was to evaluate the effects of topical 5% phenylephrine on circulation in the optic nerve head (ONH) of cynomolgus monkeys and in the central retinal artery (CRA) of aged patients. Methods In five monkeys, ONH tissue blood velocity (NBONH), determined using the laser speckle method, and intraocular pressure (IOP), blood pressure (BP), and pulse rate (PR) were measured...
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