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We wished to establish the functional identity of Nav1.6-expressing myenteric neurons of the guinea pig proximal colon by determining the extent of colocalization of Nav1.6 and selected neurochemical markers. Nav1.6-like immunoreactivity (-li) was primarily localized to the hillock and initial segments of myenteric neurons located near junctions with internodal fiber tracts. Immunoreactivity for Na...
Our purpose was to identify Nav1.2-expressing myenteric neurons of the small and large intestine of the guinea pig by using antibodies directed against Nav1.2 and selected neurochemical markers. Nav1.2-like immunoreactivity (-li) co-localized with immunoreactivity for choline acetyltransferase in all regions, representing 45%–67% of Nav1.2-positive neurons. Nav1.2-li co-localized with immunoreactivity...
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