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AbstractThe mechanism of early dorso-ventral axis specification in zebrafish embryos is not well understood. While -catenin has been clearly implicated as a determinant of the axis, the factors upstream and downstream of -catenin in this system are not defined. Unlike in Xenopus, where a sperm-induced cortical rotation is used to localize -catenin on the future dorsal side of the embryo, zebrafish...