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We have assessed the effect of 10∶1 lossy (JPEG) compression on six board-certified radiologists’ ability to detect three commonly seen abnormalities on chest radiographs. The study radiographs included 150 chest radiographs with one of four diagnoses: normal (n=101), pulmonary nodule (n=19), interstitial lung disease (n=19), and pneumothorax (n=11). Before compression, these images were printed on...