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The plasma membrane Ca2+ ATPase 2 (PMCA2) is necessary for auditory transduction and serves as the primary Ca2+ extrusion mechanism in auditory stereocilia bundles. To date, studies examining PMCA2 in auditory function using mutant mice have focused on the phenotype of late adolescent and adult mice. Here, we focus on the changes of PMCA2 in the maturation of auditory sensitivity by comparing auditory...