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The glutathione S-transferases (GSTs) are phase II xenobiotic metabolizing enzymes known to be involved in the detoxification of carcinogens and anticancer drugs. Individual genetic variation linked to inherited polymorphisms of GSTT1 and GSTM1 leading to a complete loss of enzyme activity could expose subjects to develop cancer or to induce drug resistance. Indeed, despite the impressive results...
Les Fusarium sont des champignons filamenteux saprophytes du sol, des plantes et du milieu extérieur et responsables d’infections localisées ou disséminées. Le diagnostic repose sur les hémocultures et la biopsie cutanée. La fusariose disséminée est une infection fongique rare et grave, touchant particulièrement les patients immunodéprimés neutropéniques. Les possibilités thérapeutiques sont limitées...
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