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Zebrafish have proven to be a crucial model for biological elucidations, especially heart-disease studies, owing to their remarkable regeneration capacity. Other than conventional methods, monitoring of electrocardiogram (ECG) has shown promising results recently; however, experiments were usually carried out with sedated fish, resulting in affected signals. In this work, wireless power transfer (WPT)...
This paper reports polymer-based apparatus with embedded flexible thin-film electrodes to monitor electrocardiogram (ECG) of zebrafish under mild or zero anesthesia. The apparatus were made of polydimethylsiloxane (PDMS) using the molding technique with molds formed by 3D printing. The system is capable of acquiring intrinsic ECG from multiple fish simultaneously, thus introducing a novel method to...
Heart diseases have been the leading cause of death in the developed world, partially due to failure to adequately replace lost ventricular myocardium from ischemia-induced infarct. Adult mammalian ventricular cardiomyocytes have a limited capacity to divide, and this proliferation is insufficient to overcome the significant loss of myocardium from ventricular injury. Unlike mammalian hearts, zebrafish...
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