Search results for: Chen Chen

Items from 1 to 20 out of 3,697 results

article

Anomalous photovoltaic effect in Bi(Ni_2/3Ta_1/3)O₃‐PbTiO₃ ferroelectric solid solutions

Dongfang Pang, Xitao Liu, Xiang He, Chen Chen, more

Journal of the American Ceramic Society > 102 > 6 > 3448 - 3456

Dense Bi(Ni_2/3Ta_1/3)O₃‐PbTiO₃ (BNT‐PT) ceramics were prepared by solid‐state reaction method. Morphotropic phase boundary between tetragonal and rhombohedral phase was observed around the composition 0.38BNT‐0.62PT, at which large photovoltages of 13.2V were obtained under 405 nm laser illumination with power density of 200 mW/cm². By B‐site Ni²⁺ ions doping, the bandgap values of BNT‐PT solid solutions...

article

Targeting the phosphorylation site of myristoylated alanine‐rich C kinase substrate alleviates symptoms in a murine model of steroid‐resistant asthma

Chien‐Neng Wang, Yu‐Chao Lin, Bo‐Chun Chang, Ching‐Hsien Chen, more

British Journal of Pharmacology > 176 > 8 > 1122 - 1134

Background and Purpose Myristoylated alanine‐rich C kinase substrate (MARCKS), a PKC substrate, facilitates mucus production and neutrophil migration. However, the effects of therapeutic procedures targeting the phosphorylation site of MARCKS on steroid‐resistant asthma and the mechanisms underlying such effects have not yet been investigated. We designed a peptide that targets the MARCKS phosphorylation...

article

Antimicrobial effect and proposed action mechanism of cordycepin against Escherichia coli and Bacillus subtilis

Qi Jiang, Zaixiang Lou, Hongxin Wang, Chen Chen

Journal of Microbiology > 2019 > 57 > 4 > 288-297

The detailed antibacterial mechanism of cordycepin efficacy against food-borne germs remains ambiguous. In this study, the antibacterial activity and action mechanism of cordycepin were assessed. The results showed that cordycepin effectively inhibited the growth of seven bacterial pathogens including both Gram-positive and Gram-negative bacterial pathogens; the minimum inhibitory concentrations (MIC)...

article

Mutagenesis of seed storage protein genes in Soybean using CRISPR/Cas9

Chenlong Li, Vi Nguyen, Jun Liu, Wenqun Fu, more

BMC Research Notes > 2019 > 12 > 1 > 1-7

Objective Soybean seeds are an important source of vegetable proteins for both food and industry worldwide. Conglycinins (7S) and glycinins (11S), which are two major families of storage proteins encoded by a small family of genes, account for about 70% of total soy seed protein. Mutant alleles of these genes are often necessary in certain breeding programs, as the relative abundance of these protein...

article

Facile preparation of cellulose–attapulgite nanocomposite hydrogel for dye adsorption

Xiaoyu Chen, Chen Chen, Jie Zhu

Iranian Polymer Journal > 2019 > 28 > 4 > 347-359

Attapulgite is a kind of silicate with a nano-sized rod-like morphology. In this research, a novel nanocomposite hydrogel based on cellulose and attapulgite was fabricated by a facile method and its adsorption properties for methylene blue were investigated. First, cellulose was dissolved in 7 wt% NaOH/12 wt% urea solution within 2 min, and then cellulose was cross-linked with sodium alginate by epichlorohydrin...

article

Ranolazine prevents pressure overload‐induced cardiac hypertrophy and heart failure by restoring aberrant Na⁺ and Ca²⁺ handling

Jiali Nie, Quanlu Duan, Mengying He, Xianqing Li, more

Journal of Cellular Physiology > 234 > 7 > 11587 - 11601

Background Cardiac hypertrophy and heart failure are characterized by increased late sodium current and abnormal Ca²⁺ handling. Ranolazine, a selective inhibitor of the late sodium current, can reduce sodium accumulation and Ca ²⁺ overload. In this study, we investigated the effects of ranolazine on pressure overload‐induced cardiac hypertrophy and heart failure in mice. Methods and Results Inhibition...

article

Atomically Dispersed Ruthenium Species Inside Metal–Organic Frameworks: Combining the High Activity of Atomic Sites and the Molecular Sieving Effect of MOFs

Shufang Ji, Yuanjun Chen, Shu Zhao, Wenxing Chen, more

Angewandte Chemie > 131 > 13 > 4315 - 4319

Incorporating atomically dispersed metal species into functionalized metal–organic frameworks (MOFs) can integrate their respective merits for catalysis. A cage‐controlled encapsulation and reduction strategy is used to fabricate single Ru atoms and triatomic Ru₃ clusters anchored on ZIF‐8 (Ru₁@ZIF‐8, Ru₃@ZIF‐8). The highly efficient and selective catalysis for semi‐hydrogenation of alkyne is observed...

article

Atomically Dispersed Ruthenium Species Inside Metal–Organic Frameworks: Combining the High Activity of Atomic Sites and the Molecular Sieving Effect of MOFs

Shufang Ji, Yuanjun Chen, Shu Zhao, Wenxing Chen, more

Angewandte Chemie International Edition > 58 > 13 > 4271 - 4275

article

Exploration of the role of anti‐Mullerian hormone and LH/FSH ratio in diagnosis of polycystic ovary syndrome

Minh Tam Le, Viet Nguyen Sa Le, Dinh Duong Le, Vu Quoc Huy Nguyen, more

Clinical Endocrinology > 90 > 4 > 579 - 585

Objective This study explores the role of anti‐Mullerian hormone (AMH) and LH/FSH ratio in diagnosis of polycystic ovary syndrome (PCOS). Methods In this multicentre cross‐sectional descriptive study, a total of 863 infertile women between 18 and 45 years were evaluated at three infertility centres in Vietnam and were recruited from June 2016 to June 2017. The patients were classified into two...

article

Using 3D printing technology with experiential learning strategies to improve preengineering students' comprehension of abstract scientific concepts and hands‐on ability

Hsien‐Sheng Hsiao, Jyun‐Chen Chen, Chien‐Yu Lin, Pei‐Wen Zhuo, more

Journal of Computer Assisted Learning > 35 > 2 > 178 - 187

This study combined 3D printing technology with experiential learning strategies (ELS) to design a hands‐on curriculum for preengineering students. The participants learned interdisciplinary knowledge and abstract scientific concepts through the curriculum. The study implemented a quasi‐experimental design to examine whether the students who learned using the 3D printing technology with ELS demonstrated...

article

Isoforskolin and forskolin attenuate lipopolysaccharide‐induced inflammation through TLR4/MyD88/NF‐κB cascades in human mononuclear leukocytes

Xiaohua Du, Rui Shi, Youlan Wang, Wenjuang Wu, more

Phytotherapy Research > 33 > 3 > 602 - 609

The principal active component of isoforskolin (ISOF) is from the plant Coleus forskohlii, native to China, which has attracted much attention for its biological effects. We hypothesize that ISOF and forskolin (FSK) pretreatment attenuates inflammation induced by lipopolysaccharide (LPS) related to toll‐like receptor 4 (TLR4), myeloid differentiation factor 88 (MyD88), and nuclear factor kappa B (NF‐κB)...

article

Function and dysfunction of plasma cells in intestine

Xue Wang, Gui-liang Hao, Bo-ya Wang, Chen-chen Gao, more

Cell & Bioscience > 2019 > 9 > 1 > 1-16

As the main player in humoral immunity, antibodies play indispensable roles in the body’s immune system. Plasma cells (PCs), as antibody factories, are important contributors to humoral immunity. PCs, recognized by their unique marker CD138, are always discovered in the medullary cords of spleen and lymph nodes and in bone marrow and mucosal lymphoid tissue. This article will review the origin and...

article

Genomic characterization of a novel recombinant porcine astrovirus isolated in northeastern China

Chengxue Zhao, Chen Chen, Ying Li, Shuren Dong, more

Archives of Virology > 2019 > 164 > 5 > 1469-1473

Porcine astroviruses (PAstVs), are widely distributed viruses that are highly prevalent in swine herds. In this study, a novel type 4 porcine astrovirus strain (designated as PAstV4/Tianjin/2018) was identified in a fecal sample from a diarrheal piglet in Tianjin, China and its complete genomic sequence was determined by RT-PCR. Sequence analysis showed that this strain had a capsid protein with a...

article

The Lbc gene promotes differentiation of chicken embryo stem cell into spermatogonial stem cells via the regulation of transcriptional factor Hoxa5

Jing Jin, Ruifeng Zhao, Chen Chen, Jing Zhou, more

Journal of Cellular Biochemistry > 120 > 5 > 6952 - 6961

Recently, the surface marker genes of spermatogonial stem cells (SSCs) were increasingly excavated and verified. However, few studies focused on the key genes involved in the regulation of SSCs differentiation. Our laboratory has screened the Lbc gene (GenBank accession number: XM_429585.3), which is specifically expressed on the SSCs. The aim of this study is to investigate the function of Lbc and...

article

Effects of exosomes on pre-metastatic niche formation in tumors

Yaxin Guo, Xiang Ji, Jinbo Liu, Dandan Fan, more

Molecular Cancer > 2019 > 18 > 1 > 1-11

A pre-metastatic niche is a microenvironment prepared for the colonization of circulating tumor cells in specific organs. Exosomes are extracellular vesicles with a variety of biological functions. Exosomes play an irreplaceable role in the development of pre-metastatic niches, and mainly function as communication medium. In this review, we analyzed the effects of exosomes on pre-metastatic niches...

article

Characterization of an extreme alkaline-stable keratinase from the draft genome of feather-degrading Bacillus sp. JM7 from deep-sea

Min Jin, Chen Chen, Xiongfei He, Runying Zeng

Acta Oceanologica Sinica > 2019 > 38 > 2 > 87-95

Bacillus sp. JM7, a strain isolated from the deep-sea of the South China Sea, was found to efficiently degrade 79.4% native chicken feather within 30 h. Scanning electron microscopy analysis showed that JM7 strain could gradually degrade feather by modifying the microstructure of feather keratin. A total of 25 protease genes were predicted from the draft genome of JM7 strain, among which a predicted...

article

Three-dimensional MoS₂/Graphene Aerogel as Binder-free Electrode for Li-ion Battery

Yan Zhong, Tielin Shi, Yuanyuan Huang, Siyi Cheng, more

Nanoscale Research Letters > 2019 > 14 > 1 > 1-8

Hybrid MoS₂/reduced graphene aerogels with rich micro-pore are fabricated through a hydrothermal method, followed by freeze-drying and annealing treatment. The porous structure could act as an electrode directly, free of binder and conductive agent, which promotes an improved electron transfer, and provides a 3D network for an enhanced ion transport, thus leading to an increased capacity and stable...

article

Accuracy improvement of micro‐electro‐mechanical system microwave power sensor based on self‐reference algorithm

Chenglin Li, Xiaoping Liao, Chen Chen

Microwave and Optical Technology Letters > 61 > 4 > 897 - 902

This article presents a self‐reference algorithm to improve the accuracy of micro‐electro‐mechanical system thermoelectric microwave power sensor (5‐15 GHz). The output thermovoltage of the sensor is not only a function of the input signal power, but also relates to the signal frequency, resulting in low accuracy of the sensor. In this article, a mathematical model is established for the sensor to...

article

Gallic Acid Suppresses Cardiac Hypertrophic Remodeling and Heart Failure

Xiao Yan, Yun‐Long Zhang, Liang Zhang, Lei‐Xin Zou, more

Molecular Nutrition & Food Research > 63 > 5 > n/a - n/a

Scope Gallic acid (GA) is a dietary phenolic acid found in tea, red wine, and some plants. It exhibits anti‐oxidative and anti‐inflammatory activities. Recent studies have revealed that GA has beneficial effects against several cardiovascular diseases; however, whether GA attenuates pressure‐overload‐induced cardiac hypertrophy and the underlying mechanism remains unclear. Methods and results Primary...

article

A rapid and sensitive recombinase aided amplification assay to detect hepatitis B virus without DNA extraction

Xin-xin Shen, Fang-zhou Qiu, Li-Ping Shen, Ten-fei Yan, more

BMC Infectious Diseases > 2019 > 19 > 1 > 1-5

Background Hepatitis B virus (HBV) infection is the major public health problem worldwide. In clinical practice, serological and molecular assays are the most commonly used diagnostic methods to detect HBV infection in clinical practices. Methods Here we present a rapid and sensitive recombinase aided amplification assay (RAA) to detect HBV at 39.0 °C for 30 min without DNA extraction from serum...

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INFONA - science communication portal

Search results for: Chen Chen

Anomalous photovoltaic effect in Bi(Ni_2/3Ta_1/3)O₃‐PbTiO₃ ferroelectric solid solutions

Targeting the phosphorylation site of myristoylated alanine‐rich C kinase substrate alleviates symptoms in a murine model of steroid‐resistant asthma

Antimicrobial effect and proposed action mechanism of cordycepin against Escherichia coli and Bacillus subtilis

Mutagenesis of seed storage protein genes in Soybean using CRISPR/Cas9

Facile preparation of cellulose–attapulgite nanocomposite hydrogel for dye adsorption

Ranolazine prevents pressure overload‐induced cardiac hypertrophy and heart failure by restoring aberrant Na⁺ and Ca²⁺ handling

Atomically Dispersed Ruthenium Species Inside Metal–Organic Frameworks: Combining the High Activity of Atomic Sites and the Molecular Sieving Effect of MOFs

Atomically Dispersed Ruthenium Species Inside Metal–Organic Frameworks: Combining the High Activity of Atomic Sites and the Molecular Sieving Effect of MOFs

Exploration of the role of anti‐Mullerian hormone and LH/FSH ratio in diagnosis of polycystic ovary syndrome

Using 3D printing technology with experiential learning strategies to improve preengineering students' comprehension of abstract scientific concepts and hands‐on ability

Isoforskolin and forskolin attenuate lipopolysaccharide‐induced inflammation through TLR4/MyD88/NF‐κB cascades in human mononuclear leukocytes

Function and dysfunction of plasma cells in intestine

Genomic characterization of a novel recombinant porcine astrovirus isolated in northeastern China

The Lbc gene promotes differentiation of chicken embryo stem cell into spermatogonial stem cells via the regulation of transcriptional factor Hoxa5

Effects of exosomes on pre-metastatic niche formation in tumors

Characterization of an extreme alkaline-stable keratinase from the draft genome of feather-degrading Bacillus sp. JM7 from deep-sea

Three-dimensional MoS₂/Graphene Aerogel as Binder-free Electrode for Li-ion Battery

Accuracy improvement of micro‐electro‐mechanical system microwave power sensor based on self‐reference algorithm

Gallic Acid Suppresses Cardiac Hypertrophic Remodeling and Heart Failure

A rapid and sensitive recombinase aided amplification assay to detect hepatitis B virus without DNA extraction

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