Chen Geng

article

Green Conversion of CO₂ and Propargylamines Triggered by Triply Synergistic Catalytic Effects in Metal–Organic Frameworks

Xiao‐Lei Jiang, Yue‐E Jiao, Sheng‐Li Hou, Liang‐Chen Geng, more

Angewandte Chemie International Edition > 60 > 37 > 20417 - 20423

Cyclization of propargylamines with CO₂ to obtain 2‐oxazolidone heterocyclic compounds is an essential reaction in industry but it is usually catalyzed by noble‐metal catalysts with organic bases as co‐catalysts under harsh conditions. We have synthesized a unique Cu^I/Cu^II mixed valence copper‐based framework {[(Cu^I₆I₅)Cu₃^IIL₆(DMA)₃](NO₃)⋅9DMA}_n (1) with good solvent and thermal stability, as well...

article

Green Conversion of CO₂ and Propargylamines Triggered by Triply Synergistic Catalytic Effects in Metal–Organic Frameworks

Xiao‐Lei Jiang, Yue‐E Jiao, Sheng‐Li Hou, Liang‐Chen Geng, more

Angewandte Chemie > 133 > 37 > 20580 - 20586

Cyclization of propargylamines with CO₂ to obtain 2‐oxazolidone heterocyclic compounds is an essential reaction in industry but it is usually catalyzed by noble‐metal catalysts with organic bases as co‐catalysts under harsh conditions. We have synthesized a unique Cu^I/Cu^II mixed valence copper‐based framework {[(Cu^I₆I₅)Cu₃^IIL₆(DMA)₃](NO₃)⋅9DMA}_n (1) with good solvent and thermal stability, as well...

article

Deep Learning for Automatic Differential Diagnosis of Primary Central Nervous System Lymphoma and Glioblastoma: Multi‐Parametric Magnetic Resonance Imaging Based Convolutional Neural Network Model

Wei Xia, Bin Hu, Haiqing Li, Wei Shi, more

Journal of Magnetic Resonance Imaging > 54 > 3 > 880 - 887

Background Differential diagnosis of primary central nervous system lymphoma (PCNSL) and glioblastoma (GBM) is useful to guide treatment strategies. Purpose To investigate the use of a convolutional neural network (CNN) model for differentiation of PCNSL and GBM without tumor delineation. Study Type Retrospective. Population A total of 289 patients with PCNSL (136) or GBM (153) were included,...

article

Multiparametric‐MRI‐Based Radiomics Model for Differentiating Primary Central Nervous System Lymphoma From Glioblastoma: Development and Cross‐Vendor Validation

Wei Xia, Bin Hu, Haiqing Li, Chen Geng, more

Journal of Magnetic Resonance Imaging > 53 > 1 > 242 - 250

Background Preoperative differentiation of primary central nervous system lymphoma (PCNSL) from glioblastoma (GBM) is important to guide neurosurgical decision‐making. Purpose To validate the generalization ability of radiomics models based on multiparametric‐MRI (MP‐MRI) for differentiating PCNSL from GBM. Study Type Retrospective. Population In all, 240 patients with GBM (n = 129) or PCNSL...

article

Combining SENSE and reduced field-of-view for high-resolution diffusion weighted magnetic resonance imaging

Jisu Hu, Ming Li, Yakang Dai, Chen Geng, more

BioMedical Engineering OnLine > 2018 > 17 > 1 > 1-11

Background In diffusion-weighted magnetic resonance imaging (DWI) using single-shot echo planar imaging (ss-EPI), both reduced field-of-view (FOV) excitation and sensitivity encoding (SENSE) alone can increase in-plane resolution to some degree. However, when the two techniques are combined to further increase resolution without pronounced geometric distortion, the resulted images are often corrupted...

article

Advances in intelligent diagnosis methods for pulmonary ground-glass opacity nodules

Jing Yang, Hailin Wang, Chen Geng, Yakang Dai, more

BioMedical Engineering OnLine > 2018 > 17 > 1 > 1-18

Pulmonary nodule is one of the important lesions of lung cancer, mainly divided into two categories of solid nodules and ground glass nodules. The improvement of diagnosis of lung cancer has significant clinical significance, which could be realized by machine learning techniques. At present, there have been a lot of researches focusing on solid nodules. But the research on ground glass nodules started...

chapter

Vessel segmentation using prior shape based on tensor analysis for inhomogeneous intensity and weak-edge images

Zhiyong Zhou, Chen Geng, Jisu Hu, Baotong Tong, more

2017 2nd International Conference on Image, Vision and Computing (ICIVC) > 323 - 326

2017 2nd International Conference on Image, Vision and Computing (ICIVC)

Blood vessel segmentation is a key component for various clinical applications. In this paper, we present a novel method for vessel segmentation by using a prior shape based on tensor analysis and then incorporate it in a level-set-based segmentation method. We firstly introduce the prior shape via tensor analysis, which formulates the fractional anisotropy and anisotropic character of the mechanical...

article

Direct point-based registration for precise non-rigid surface matching using Student’s-t mixture model

Zhiyong Zhou, Baotong Tong, Chen Geng, Jisu Hu, more

Biomedical Signal Processing and Control > 2017 > 33 > C > 10-18

One of the main challenges in the non-rigid surface matching is to match complex surfaces with absence of salient landmarks (marker-less) and salient structures (structure-less). We propose an accurate non-rigid surface registration method, called DSMM, to match complex surfaces based on a dense point-to-point correspondence alignment. The key idea of our approach is to model the correspondences on...

chapter

Computer aided analysis of cognitive disorder in patients with Parkinsonism using machine learning method with multilevel ROI-based features

Bo Peng, Zhiyong Zhou, Chen Geng, Baotong Tong, more

2016 9th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics (CISP-BMEI) > 1792 - 1796

2016 9th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics (CISP-BMEI)

This paper proposes to use multilevel ROI-based features and machine learning method to improve the accuracy of qualitative recognition of mild cognitive disorder in parkinsonism. 77 Parkinson's patients and 32 normal controls with neuropsychological assessments and structural magnetic resonance images from the Parkinson's Progression Markers Initiative dataset are tested. Specifically, the BrainLab...

article

Sustained methylene blue staining to guide anatomic hepatectomy for hepatocellular carcinoma: Initial experience and technical details

Cai Shou-wang, Yang Shi-zhong, Lv Wen-ping, Chen Geng, more

Surgery > 2015 > 158 > 1 > 121-127

The boundary of the target hepatic segment within the liver parenchyma cannot be marked by the use of a conventional anatomic hepatectomy approach. This study describes a novel methylene blue staining technique for guiding the anatomic resection of hepatocellular carcinoma (HCC).Between February 2009 and February 2012, anatomic hepatectomy was performed in 106 patients with HCC via a novel, sustained...

article

MicroRNA-135a and -200b, potential Biomarkers for Alzheimer׳s disease, regulate β secretase and amyloid precursor protein

Chen-geng Liu, Jin-ling Wang, Lei Li, Li-xiang Xue, more

Brain Research > 2014 > 1583 > Complete > 55-64

Amyloid precursor protein (APP) and β-site amyloid precursor protein cleaving enzyme (BACE-1) play important roles in the generation of Alzheimer׳s disease (AD), a progressive neurodegenerative disorder. In the present study, microRNA (miR) microarray was used to analyze the miR expression profiles in the hippocampi from APP/PS1 transgenic and wild type mice. The miRs with significant alteration and...

article

Structure, spectroscopy, and theory calculations on 1,3-bis((5,6-dimethyl-1H-benzo[d]imidazol-1-yl)methyl)benzene

Guang-Yue Li, Jian-Chen Geng, Cui-Hong He, Guang-Hua Cui

Journal of Molecular Structure > 2013 > 1031 > Complete > 56-60

The molecule, 1,3-bis((5,6-dimethyl-1H-benzo[d]imidazol-1-yl)methyl)benzene (short for T, C ₂₆ H ₂₆ N ₄ ), was synthesized and characterized by UV–Vis spectroscopy, infrared spectroscopy and single crystal X-ray diffraction. The molecular geometry, vibrational frequencies, absorption spectrum of the compound T have been calculated by using the density functional theory (DFT/B3LYP)...

article

Two 2D cobalt(II) coordination frameworks with unusual binodal network topology: synthesis, structures, and catalytic properties

Jian Chen Geng, Li Wei Liu, Shu Lin Xiao, Guang Hua Cui

Transition Metal Chemistry > 2013 > 38 > 2 > 143-148

Two coordination polymers, namely {[Co₂(L1)₂(btec)]∙4H₂O}_n (1) and [Co(L2)(btec)_0.5(H₂O)]_n (2) [L1 = 1,3-bis(5,6-dimethylbenzimidazole)propane, btec = 1,2,4,5-benzenetetracarboxylate, L2 = 1,2-bis(5,6-dimethylbenzimidazole-1-ylmethyl)benzene], have been synthesized and characterized by physicochemical and spectroscopic methods as well as single-crystal diffraction. The cobalt(II) atoms display different...

chapter

A novel non-contact interactive medical image viewing system

Chen Geng, Jian Yang, Tong Li, Yongtian Wang

2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops > 254 - 259

2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)

Currently, photographic film is the most commonly used medium for viewing medical images in hospitals. However, as digitalized medical images need to be printed on photographic film first, such kind of viewing pattern has an extremely limited use A homogeneous white light source is also needed to observe the anatomic structure clearly. Such observation pattern is very limited to the circumstances...

article

Assembly multi-dimensional CdII coordination architectures based on flexible bis(benzimidazole) ligands: Diversity of their coordination geometries and fluorescent properties

Cui-huan Jiao, Jian-chen Geng, Cui-hong He, Guang-hua Cui

Journal of Molecular Structure > 2012 > 1020 > Complete > 134-141

Based on three structurally related flexible bis(5,6-dimethylbenzimidazole) ligand, five novel metal–organic Cd ^II coordination architectures: from 0D to 3D structures Cd ^II complexes have been hydrothermally synthesized and structurally characterized, namely, Cd ₂ I ₄ (L1) ₂ (1), [CdCl ₂ (L1)] _n (2), [CdCl ₂ (L2)] _n (3), {[Cd(chdc)(L2)...

article

Synthesis, Crystal Structures, and Catalytic Properties of Silver(I) and Cobalt(II) Coordination Polymers Based on Flexible Bis(benzimidazole) with Pyridine‐2, 6‐Dicarboxylate

Jian‐Chen Geng, Li Qin, Xu Du, Shu‐Lin Xiao, more

Zeitschrift für anorganische und allgemeine Chemie > 638 > 7‐8 > 1233 - 1238

Two coordination polymers, [Ag₂(pydca)(bbbi)₂]_n (1) and [Co₂(pydca)₂(bbbi)₃]_n·nH₂O (2) [pydca = pyridine‐2, 6‐dicarboxylate, bbbi = 1, 1′‐(1, 4‐butylene)bis‐1H‐benzimidazole)] were hydrothermally synthesized and characterized by elemental analysis, IR spectroscopy, TG, PXRD, and single‐crystal X‐ray diffraction. Compound 1 features a one‐dimensional helical chain structure bridged by bbbi ligand,...

article

Systematic comparison of cervical and extra-cervical surgical approaches for endoscopic thyroidectomy

Chen Geng-Zhen, Zhang Xuan, Shi Wei-Lin, Zhuang Ze-Rui, more

Surgery Today > 2012 > 42 > 9 > 835-841

Objective To evaluate the clinical application of different surgical approaches for endoscopic thyroidectomy and provide more rational treatment criteria. Methods Collect all randomized controlled trials, multi-center studies, clinical controlled trials, clinical trials and other comparative studies of endoscopic thyroidectomy with a large sample size in different databases through an established...

article

Synthesis, crystal structures and catalytic properties of copper(II) and cobalt(II) coordination polymers based on a flexible benzimidazole ligand

Jian-chen Geng, Li Qin, Cui-hong He, Guang-hua Cui

Transition Metal Chemistry > 2012 > 37 > 6 > 579-585

Two coordination polymers, namely [Cu(L)₂]·(NO₃)₂ (1) and [Co(L)(chdc)]·2H₂O (2) [(chdc = 1,4-cyclohexanedicarboxylate, L = 1,3-bis-(5,6-dimethylbenzimidazole-1-yl-methylene)-benzene], based on a flexible 5,6-dimethylbenzimidazole ligand have been synthesized and characterized by physico-chemical and spectroscopic methods and single-crystal diffraction. Complex 1 shows a 2D (4,4) network structure...

article

Age-dependent down-regulation of DNA polymerase δ1 in human lymphocytes

Jin-Ling Wang, Hong-Lin Guo, Pei-Chang Wang, Chen-Geng Liu

Molecular and Cellular Biochemistry > 2012 > 371 > 1-2 > 157-163

Aging progress and degeneracy of functional activity are mainly attributed to the decreased DNA repair potential. DNA polymerase (pol) δ activity plays an essential role in genome stability by virtue of its crucial DNA replication and repair capacity. To order to clarify the role of DNA pol δ in aging progression, we firstly examined the expressions of its catalytic subunit named DNA pol δ1 in human...

article

Synthesis, crystal structures and catalytic properties of two 1D cobalt(II) coordination polymers

Cui-huan Jiao, Cui-hong He, Jian-chen Geng, Guang-hua Cui

Transition Metal Chemistry > 2012 > 37 > 1 > 17-23

Two new cobalt(II) coordination polymers, namely [Co_1.5(PhCOO)₃(bbbm)_1.5(H₂O)]_n (1) and [Co(chdc)(bbbm)]_n (2) (bbbm = 1,1′-(1,4-butanediyl)bis-1H-benzimidazole, H₂chdc = 1,4-cyclohexanedicarboxylic acid), have been synthesized and structurally characterized by single crystal X-ray diffraction. The cobalt(II) centers display different environments, with trigonal–bipyramidal and octahedral geometries...

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Search results for: Chen Geng

Green Conversion of CO₂ and Propargylamines Triggered by Triply Synergistic Catalytic Effects in Metal–Organic Frameworks

Green Conversion of CO₂ and Propargylamines Triggered by Triply Synergistic Catalytic Effects in Metal–Organic Frameworks

Deep Learning for Automatic Differential Diagnosis of Primary Central Nervous System Lymphoma and Glioblastoma: Multi‐Parametric Magnetic Resonance Imaging Based Convolutional Neural Network Model

Multiparametric‐MRI‐Based Radiomics Model for Differentiating Primary Central Nervous System Lymphoma From Glioblastoma: Development and Cross‐Vendor Validation

Combining SENSE and reduced field-of-view for high-resolution diffusion weighted magnetic resonance imaging

Advances in intelligent diagnosis methods for pulmonary ground-glass opacity nodules

Vessel segmentation using prior shape based on tensor analysis for inhomogeneous intensity and weak-edge images

Direct point-based registration for precise non-rigid surface matching using Student’s-t mixture model

Computer aided analysis of cognitive disorder in patients with Parkinsonism using machine learning method with multilevel ROI-based features

Sustained methylene blue staining to guide anatomic hepatectomy for hepatocellular carcinoma: Initial experience and technical details

MicroRNA-135a and -200b, potential Biomarkers for Alzheimer׳s disease, regulate β secretase and amyloid precursor protein

Structure, spectroscopy, and theory calculations on 1,3-bis((5,6-dimethyl-1H-benzo[d]imidazol-1-yl)methyl)benzene

Two 2D cobalt(II) coordination frameworks with unusual binodal network topology: synthesis, structures, and catalytic properties

A novel non-contact interactive medical image viewing system

Assembly multi-dimensional CdII coordination architectures based on flexible bis(benzimidazole) ligands: Diversity of their coordination geometries and fluorescent properties

Synthesis, Crystal Structures, and Catalytic Properties of Silver(I) and Cobalt(II) Coordination Polymers Based on Flexible Bis(benzimidazole) with Pyridine‐2, 6‐Dicarboxylate

Systematic comparison of cervical and extra-cervical surgical approaches for endoscopic thyroidectomy

Synthesis, crystal structures and catalytic properties of copper(II) and cobalt(II) coordination polymers based on a flexible benzimidazole ligand

Age-dependent down-regulation of DNA polymerase δ1 in human lymphocytes

Synthesis, crystal structures and catalytic properties of two 1D cobalt(II) coordination polymers

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