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Objective To identify the commonalities between rheumatoid arthritis (RA) and diabetes mellitus (DM) to understand the mechanisms of Chinese medicine (CM) in different diseases with the same treatment. Methods A text mining approach was adopted to analyze the commonalities between RA and DM according to CM and biological elements. The major commonalities were subsequently verified in RA and DM rat...
To explore the regularity of clinical medication of Gastro-esophageal reflux disease (GERD) through text mining approach. Literatures on GERD in SinoMed(Chinese biomedical literature service system) were collected. Results: BANXIA, CHAIHU and HUANGLIAN were commonly used Chinese herbs in sequence from high to low, the network of Chinese herbs, symptoms and patterns could be established. Conclusion:...
As the fifth most common malignancy, liver cancer has a high incidence. Chinese herbal medicine (CHM) has been an integral part of traditional Chinese medicine (TCM) for thousands of years. Many herbal formulae have been used in treating liver cancer and proved to be safe and effective in some degree. Yet the principles of treating liver cancer with CHMs are hard to manage due to the complexity of...
It is a long histroy that use of acupuncture treatment coronary heart disease (CHD) which belongs to Xiong Bi in Traditional Chinese Medicine (TCM). In this paper, application of acupuncture on CHD treatment was analyzed by text mining. The study was focused on the fields of meridian, acupoints, acupuncture method and constructed the associated network of them. By analyzing the network, we found that...
Acupoint application therapy is one of the Traditional Chinese medicine (TCM) external therapies, which has been used for coronary heart disease (CHD) treatment for a long time. The prescription of acupoint application therapy includes both Chinese herbal medicines (CHMs) and acupoints. This study aims to reveal the basic rules of acupoint selection in acupoint application therapy on CHD treatment...
Mammary gland hyperplasia (MGH) is a kind of endocrine disorder diseases, which is usually characterized by lump and pain in breast and an increased risk event of breast cancer. The complementary therapies of Traditional Chinese Medicine (TCM) play important roles in MGH treatment. This study analyzed the application of the TCM external therapy and food therapy by text mining. Subsequently, suitable...
Tinnitus is the most common medical symptom that can be debilitating. Chinese herbal medicines (CHMs) play important roles in tinnitus treatment. This study analyzed the most frequently prescribed herbs used to treat tinnitus and the molecular mechanisms of therapeutic effects of these CHMs by text mining and bioinformatics technique. Results showed that pinellia ternate (Banxia) and gastrodin (Tianma)...
Hypertension becomes a major public health problem due to its serious morbidity and mortality and serious cardiovascular, cerebrovascular and kidney complications. The complementary therapies of Traditional Chinese Medicine (TCM) play important roles in hypertension treatment. Acupuncture, as an important component in TCM, is frequently used in treatment hypertension. In this paper, we mined the data...
The morbidity of Diabetes mellitus (DM) is increasing at a speed of 3.2% per year globally, and involving people of all ages, especially the ones who are more than fifties. Most of the patients suffer from the Non-insulin-dependent type which is also called type 2 diabetes mellitus. Traditional Chinese Medicine (TCM) has accumulated rich experience in curing DM which is considered as “Xiaoke” in TCM...
Acne is the most common chronic inflammatory skin disease in adolescents and young adults. Many Chinese herbal medicines (CHMs) have been used in the treatment of acne and were proved to be effective and safe. There is growing need to investigate which CHMs are the most frequently prescribed herbs used to treatment acne and what were the molecular mechanisms of therapeutic effects of these CHMs. So...
It is a still a world-wide challenge that hypertensive patients maintain a satisfactory blood pressure control. In TCM practice, traditional physical therapy has shown beneficial to blood pressure (BP) controlling. As the amount of bio medical data in leading databases (i.e. SinoMed, etc.) is growing at an exponential rate, it might be possible to get something meaningful through the techniques developed...
Hypertension becomes a major public health problem due to its high prevalence and serious complications. The complementary therapies of Traditional Chinese Medicine (TCM) play important roles in hypertension treatment. This study analyzed the application of the TCM external therapy and food therapy by text mining. Subsequently, suitable techniques and methods which were frequently used on hypertension...
In traditional Chinese medicine, rules of Li-Fa-Fang-Yao is of critical importance in clinical practices. Li-Fa-Fang-Yao, which means principles, methods, formulae, and Chinese herbal medicines respectively, indicate the four basic steps of diagnosis and treatment: determining the cause, mechanism and location of the disease according to the medical theories and principles, then deciding the treatment...
Non-alcoholic fatty liver disease (NAFLD) is a kind of prevalence diseases. Traditional Chinese medicine (TCM) has better efficacy on treating NAFLD. But there are also not known about the critical pathogenesis and the corresponding biological factors. Regarding this, we addressed a text mining approach to analyze the pattern profile, rule of medication, and the pathological factors of NAFLD from...
It is well known that acupuncture treatment has an effect on patients with ischemie cerebrovascular disease. This study was aimed to summarize the basic laws of acupoints of ischemie cerebrovascular disease in acupuncture treatment using text mining techniques. First, we proposed the text-mining-based method to collect related literatures about acupuncture treatment of ischemie cerebrovascular disease...
Checking the consistency of knowledge items between textbook and clinical practice is very important for traditional Chinese medicine (TCM). According to the textbook of internal medicine of TCM, rheumatoid arthritis (RA) is a disease with four syndromes (also called pattern) and Feng-Han-Shi-Bi is the major one. Bisimulation is an equivalence relationship/method in formal methods which can be used...
Single Chinese herbal medicine is the basic element in traditional Chinese medicine's clinical treatment against disease. Then, it is an interesting and meaningful task to acquire knowledge of a single Chinese herbal medicine within the framework of traditional Chinese medicine (TCM). In this paper, based on the knowledge of TCM, we explored the association rules of Danggui (Angelica sinensis in Latin)...
Single Chinese herbal medicine (CHM) is the basic element in the formulae of traditional Chinese medicine (TCM). How to acquire knowledge of a single CHM within the framework of TCM is a meaningful task. In TCM, Radix Astragali (RA) is frequently and widely used in clinical practice. In order to explore the associating rules between prescription and syndrome on RA with text mining technique, we downloaded...
Diabetes mellitus, or simply diabetes, is a group of metabolic diseases in which a person has high blood sugar, either because the body does not produce enough insulin, or because cells do not respond to the insulin that is produced. In traditional Chinese medicine (TCM), diabetes mellitus is called “Sweet Urine Disease”. Over several thousand years of clinical research and theoretical thoughts, some...
Urinary tract infections (UTIs) are among the most common infectious diseases occurring in either the community or healthcare setting. Approximately one third of all women have had at least one physician-diagnosed uncomplicated UTI by the age of 26 years. A broad range of pathogens can cause complicated UTI. Escherichia coli remains the most common organism causing UTI. Antimicrobial resistance is...
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