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Rapid and effective injection of functional nanobeads into a specific living cell with high cell viability is one of the most important issues for single cell analysis. This paper reports a novel method of injecting single magnetic nanobeads into a living Madin-Darby canine kidney (MDCK) cell using a continuous-wave near infrared laser. Experimental results demonstrated the successful injection of...
Optical heating of metallic nanoparticles is of great significance to biological and biomedical applications, such as gene/molecule delivery and intracellular microenvironment measurement. In this study, we propose to employ optical heating of metallic nanoparticles to achieve fast injection of single nanoscale sensor into living cells. The nanoscale sensor consists of polystyrene bead, which is embedded...
We synthesized a novel multi-fluorescence sensor which can respond to both pH and temperature. This kind of sensor was based on amino-polystyrene microbeads and two different fluorescent indicators (Rhodamine B and FITC) were applied simultaneously to synthesize the multi-sensor. Rhodamine B shows an excellent linear relationship between the relative fluorescent intensity and temperature while it...
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