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Background The notion of centrality is used to identify “important” nodes in social networks. Importance of nodes is not well-defined, and many different notions exist in the literature. The challenge of defining centrality in meaningful ways when network edges can be positively or negatively weighted has not been adequately addressed in the literature. Existing centrality algorithms also have a second...
Large-scale biological networks such as gene regulatory [1] and PPI [2] have become commonplace through systems biology. Figure 1 shows a microbial social network [3], which attempts to infer interactions between microbes within a community from metagenomics studies. In particular this is a co-occurence network [4], where green/red edges respectively represent positive/negative correlations, or how...
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