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Micro-PET/CT has been widely used for brain imaging in diverse preclinical studies using mouse models. The precise brain extraction is an important pre-procedure to quantify the brain function based on micro-PET/CT images. In this study, we explored an automatic framework based on a modified level-set method (MLS) for mouse brain extraction in micro-PET/CT images. In the proposed MLS method, the initial...
Zebrafish has become one of the most popular and useful models in cell biology, development, and drug discovery. Because zebrafish embryo is transparent and can be observed under microscope without fixation, it is increasingly used in high-throughput screening. The small size of zebrafish embryos allows users to image them in a 96- or 384-well plate under various conditions, in turn, generating such...
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