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We present a handheld device for the simple, stable, high-throughput, and viable circulating tumor cell (CTC) isolation with the whole blood processing capacity of 3.3ml/hr. The device uses the microfabricated tapered-slit filters having wider slit entrances and gradually narrower slit exits. Compared to the conventional straight-slit filters, the tapered-slit filters are capable to increase blood...
We present a high-efficient particle trapping chip, where a wide and uniform slit is formed by a deformable membrane barrier with air bubble plugs. The air bubble plugs remained in the extended microchannel during sample filling process, block the particle passage at the both side ends of the membrane, thus all particles flow through the uniform slit gap. Therefore, high-efficient particle trapping...
In this paper an improved Lab-on-a-Chip device has been proposed for focusing the particle at the center of the channel to separate the desired particles from the main stream at the exit. The design methodology is kept simple and a two fluidic port device with geometric description is proposed. The induced dielectric force responsible for focusing particle is accomplished by means of two electrodes...
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