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Background The chromatin remodelers of the SWI/SNF family are critical transcriptional regulators. Recognition of lysine acetylation through a bromodomain (BRD) component is key to SWI/SNF function; in most eukaryotes, this function is attributed to SNF2/Brg1. Results Using affinity purification coupled to mass spectrometry (AP–MS) we identified members of a SWI/SNF complex (SWI/SNFTt) in Tetrahymena thermophila...
How the eukaryotic cell specifies distinct chromatin domains is a central problem in molecular biology. The ciliate protozoan Tetrahymena thermophila features a separation of structurally and functionally distinct germ-line and somatic chromatin into two distinct nuclei, the micronucleus (MIC) and macronucleus (MAC) respectively. To address questions about how distinct chromatin states are assembled...
This paper presents the design of low power Voltage Controlled Oscillator with differential stages. Circuit uses multiple pass loop architecture having primary and secondary (auxiliary feed forward) loops. In delay cell positive feedback is used with cross coupled regenerative PMOS load, due to that power consumption reduces. For best tuning range multiple delay path is used. Measurement shows that...
This paper presents stochastic convergence analysis of particle swarm optimization algorithm involving randomness and applying the results to the Analog RF Circuits to optimize the circuit parameters. In every iteration, each particle position is represented as vector and the standard particle swarm algorithm determined by positive real tipple {w,c1,c2}. Comparisons for convergence are presented with...
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