Search results for: Fen-fen Liu

Items from 1 to 7 out of 7 results

article

Nkx6.1 Is Essential for Maintaining the Functional State of Pancreatic Beta Cells

Brandon L. Taylor, Fen-Fen Liu, Maike Sander

Cell Reports > 2013 > 4 > 6 > 1262-1275

Recently, loss of beta-cell-specific traits has been proposed as an early cause of beta cell failure in diabetes. However, the molecular mechanisms that underlie the loss of beta cell features remain unclear. Here, we identify an Nkx6.1-controlled gene regulatory network as essential for maintaining the functional and molecular traits of mature beta cells. Conditional Nkx6.1 inactivation in adult...

article

Methionine and choline regulate the metabolic phenotype of a ketogenic diet

Pavlos Pissios, Shangyu Hong, Adam Richard Kennedy, Deepthi Prasad, more

Molecular Metabolism > 2013 > 2 > 3 > 306-313

Low-carbohydrate ketogenic diets are commonly used as weight loss alternatives to low-fat diets, however the physiological and molecular adaptations to these diets are not completely understood. It is assumed that the metabolic phenotype of the ketogenic diet (KD) is caused by the absence of carbohydrate and high fat content, however in rodents the protein content of KD affects weight gain and ketosis...

article

Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma

Janel L. Kopp, Guido von Figura, Erin Mayes, Fen-Fen Liu, more

Cancer Cell > 2012 > 22 > 6 > 737-750

Tumors are largely classified by histologic appearance, yet morphologic features do not necessarily predict cellular origin. To determine the origin of pancreatic ductal adenocarcinoma (PDA), we labeled and traced pancreatic cell populations after induction of a PDA-initiating Kras mutation. Our studies reveal that ductal and stem-like centroacinar cells are surprisingly refractory to oncogenic transformation,...

chapter

The research on development of small and medium-sized technology enterprises related to government and entrepreneurs

Han-bing Liang, Fen-fen Liu

2011 International Conference on Electronics, Communications and Control (ICECC) > 3427 - 3431

2011 International Conference on Electronics, Communications and Control (ICECC)

This paper analyses cooperation interaction relationship between government, entrepreneurs and tech SMEs based on triple spiral theory. By the analytic hierarchy process and regression analysis method, this paper studies the influential factors of development of tech SMEs, and gets the conclusion that government's policy and the entrepreneurs' professional quality are the important endogenous and...

article

Dysregulation of the Mesolimbic Dopamine System and Reward in MCH−/− Mice

Pavlos Pissios, Lauren Frank, Adam R. Kennedy, Douglas R. Porter, more

Biological Psychiatry > 2008 > 64 > 3 > 184-191

The hypothalamic neuropeptide melanin-concentrating hormone (MCH) plays a critical role in energy homeostasis. Abundant expression of the MCH receptor is observed outside the hypothalamus, especially in the dorsal and the ventral striatum, raising the possibility that MCH modulates the function of the midbrain dopamine neurons and associated circuitry.The MCH receptor 1 (MCHR1) expression was assessed...

article

Skeletal deformities of acardius anceps: the gross and imaging features

C.-P. Chen, Shin-Lin Shih, Fen-Fen Liu, Sheau-Wen Jan, more

Pediatric Radiology > 1997 > 27 > 3 > 221-225

Abstract A morphology based imaging review is presented of the characteristic skeletal deformities associated with acardius anceps in three acardiac twins. These fetuses demonstrated poorly developed skulls, limb reduction defects, and phocomelia of the upper limbs, as well as narrow thoracic cages with or without the complete development of ribs, clavicles, scapulae, and cervical, thoracic, or lumbar...

article

In utero urinary bladder perforation, urinary ascites, and bilateral contained urinomas secondary to posterior urethral valves: clinical and imaging findings

C.-P. Chen, Shin-Lin Shih, Fen-Fen Liu, Sheau-Wen Jan, more

Pediatric Radiology > 1997 > 27 > 1 > 3-5

Abstract We report on a rare in utero appearance of urinary bladder perforation, urinary ascites, and bilateral contained urinomas secondary to posterior urethral valves. The findings on prenatal sonography, postnatal voiding cystourethrography, and magnetic resonance imaging are described.

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Search results for: Fen-fen Liu

Nkx6.1 Is Essential for Maintaining the Functional State of Pancreatic Beta Cells

Methionine and choline regulate the metabolic phenotype of a ketogenic diet

Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma

The research on development of small and medium-sized technology enterprises related to government and entrepreneurs

Dysregulation of the Mesolimbic Dopamine System and Reward in MCH−/− Mice

Skeletal deformities of acardius anceps: the gross and imaging features

In utero urinary bladder perforation, urinary ascites, and bilateral contained urinomas secondary to posterior urethral valves: clinical and imaging findings

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INFONA - science communication portal

Search results for: Fen-fen Liu

Nkx6.1 Is Essential for Maintaining the Functional State of Pancreatic Beta Cells

Methionine and choline regulate the metabolic phenotype of a ketogenic diet

Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma

The research on development of small and medium-sized technology enterprises related to government and entrepreneurs

Dysregulation of the Mesolimbic Dopamine System and Reward in MCH−/− Mice

Skeletal deformities of acardius anceps: the gross and imaging features

In utero urinary bladder perforation, urinary ascites, and bilateral contained urinomas secondary to posterior urethral valves: clinical and imaging findings

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