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In this study, the effects of UCA injection and ultrasound pressure on BBB disruption were investigated. Sonications were applied with an ultrasound frequency of 1 MHz, a burst length of 10 ms at 1% duty cycle, and a repetition frequency of 1 Hz. The duration of the whole sonication was 30 s. In-vivo experiments, twelve male Wistar rats were sonicated with four different UCA injections (0, 30, 60,...
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