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Microfabricated nozzle-array devices have been newly developed to form multilamellar lipid tubes (MLTs), in which the dried films of phospholipids are swelled through the micronozzles and the fluidic shear-stress is utilized not only to control the morphology of MLTs but also to store deformation energy producing self-actuating MLTs. MLTs were successfully formed with high reproducibility and the...
Separation/purification of nuclei from cells is a critical process required for medical and biochemical research applications. Here we report a microfluidic device to isolate cell nucleus by utilizing the concept of hydrodynamic filtration to chemically treat cells. When a cell suspension is continuously introduced into a microchannel (main channel) having multiple side channels, cells flow through...
Sterilization of micro-organism, such as Escherichia coli, is experimentally investigated by using microplasma. Microplasma is suitable for practical application of sterilization, since its discharge voltage is low and its apparatus could be small and inexpensive. In this study, Gram-negative Escherichia coli HB101 and Gram-positive Bacillus subtilis JCB 20036 are used as the target to be sterilized...
The abundance of bacterial cells should be routinely monitored to maintain microbiological quality control of drinking water. We investigated the ability of a newly designed microfluidic device to determine bacterial numbers in freshwater at a density in the order of 104 cells/ml. A microfluidic device was designed and fabricated by polydimethylsiloxane (PDMS) and a thin glass slide (size: 48 mmtimes23...
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