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Centrifugally Tensioned Metastable Fluid Detector systems (CTMFDs) have a number of valuable advantages over other conventional, state of the art systems (e.g., 3He tubes). CTMFDs can be configured to attain intrinsic efficiencies over 90% for neutron energies from the thermal to the fast region (ev to MeV). TMFDs can detect alpha and fission recoil interactions exceeding 10 times lower activity than...
Purdue University is developing novel, multi-purpose tension metastable fluid nuclear particle detectors (TMFDs) by which multiple types of nuclear particles can be detected with high (90%+) intrinsic efficiency, directional specificity, spectroscopic capability, rapid response, large standoff and significant cost-savings compared with state-of-the-art systems. This paper presents uses of these novel...
Due to He-3 shortages as well as other fundamental limitations of 60-y nuclear power technology being adapted for present-day sensor needs, transformational nuclear particle sensor system developments have sponsored by DARPA, DoE, DHS and NSF. These systems dispense with need for conventional He-3, liquid scintillation or solid-state devices. The novel systems detect a variety of radiation types via...
Transformational nuclear particle sensor systems have been developed for detecting a variety of radiation types via interactions with ordinary fluids such as water and acetone placed under metastable states of tensioned (yes, sub-zero or below-vacuum) liquid pressures at room temperature. Advancements have resulted in the development of lab-scale prototypes which provide real-time directionality information...
Recent advances in the study of the tumor microenvironment have revealed significant interaction between tumor cells and their surrounding stroma in model systems. We have previously shown that two distinct stromal signatures derived from a macrophage (CSF1) response and a fibroblastic (DTF-like) response are present in subsets of invasive breast cancers and show a correlation with clinical outcome...
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