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Synthetic biologists design genetic logic circuit using living cells. A challenge in this task is the difficulty in constructing bigger logic circuits with several living cells due to the crosstalk effect among the biological cells. In order to remove the crosstalk effect, current practice is to use separate chambers on a flow-based microfluidic biochip to isolate each reaction zone. The state-of-the-art...
Digital microfluidic biochips (DMFBs) play an important role in the healthcare industry due to its advantages such as low-cost, portability, and efficiency. According to the recent market report, the growth of biochips market is twice than before. However, as the enormous business opportunities grow, piracy attacks, which are exploited by unscrupulous people to gain illegal profits, become a severe...
With the trend of outsourcing fabrication, split manufacturing is regarded as a promising way to both provide the high-end nodes in untrusted external foundries and protect the design from potential attackers. However, in this work, we show that split manufacturing is not inherently secure. A hardware trojan attacker can still discover necessary information with a simulated annealing based attack...
Analog layout design has been a manual, time-consuming, and error-prone task for decades. To speed up layout design time for a new design, analog layout designers prefer referring to legacy designs and layouts rather than starting from scratch, or thoroughly applying placement and routing tools because legacy layouts contain pretty much design expertise. Motivated by such layout design process, this...
Advances in flow-based microfluidic biochips offer tremendous potential for biochemical analyses and clinical diag-nostics. However, the adoption of flow-based biochips is hampered by defects that are especially common for chips fabricated using soft lithography techniques. Recently published work on fault detection in flow-based biochips is based on logic-circuit modeling of the microfluidic channels...
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