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Sjögren’s syndrome (SS) is a chronic autoimmune disease that mainly damages the salivary and lacrimal glands. Immune complex (IC) formation triggers local inflammation through IC deposition and decreased antigen function. Some ICs can leak from the lesion and into the saliva, but no salivary ICs have been reported to date. We used immune complexome analysis to comprehensively identify antigens incorporated...
Background Interaction between cancer cells and fibroblasts mediated by extracellular matrix metalloproteinase inducer (emmprin, CD147) is important in the invasion and proliferation of cancer cells. However, the exact mechanism of emmprin mediated stimulation of matrix metalloprotease-2 (MMP-2) production from fibroblasts has not been elucidated. Our previous studies using an inhibitory peptide against...
The aim of transfer learning is to improve prediction accuracy on a target task by exploiting the training examples for tasks that are related to the target one. Transfer learning has received more attention in recent years, because this technique is considered to be helpful in reducing the cost of labeling. In this paper, we propose a very simple approach to transfer learning: TrBagg, which is the...
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