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In this paper, we present an approach for modeling computational genetic regulatory networks with multi-threshold protein concentration and combinatorial gene–protein interactions. We first present a gene automata model that describes the activities of a single gene, and discuss the construction of a network automaton model that describes the complete behavior of a gene network. To model the gene–protein...
This article presents a formal framework for modeling computational genetic regulatory networks as automata, with multi-threshold protein concentration and combinatorial logical gene-protein interactions. By computing the intersection of the languages generated by these automata we obtain the complete set of pathways in a gene network. We illustrate the effectiveness of our framework in the modeling...
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