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Myelin biogenesis is a complex process involving coordinated exocytosis, endocytosis, mRNA transport, and cytoskeletal dynamics. Although abnormalities of myelin are common in lysosomal storage diseases, our understanding of the role of lysosomes in the formation and maintenance of myelin is still limited. Here, we show that late endosomes/lysosomes in Schwann cells contain abundant myelin protein...
With the rapid advance of location-based services (LBS) and online map services, it is now more feasible than before to collect the geo-referenced individual level data. However, privacy is always an issue whenever personal location is traced and recorded. This paper proposes a reactive location-based service to collect and process individual location data by different privacy policies. The reactive...
Using vehicles as probes is a flexible and low-cost way to obtain real-time traffic information. A key problem of using probe vehicles is to determine vehicle's sampling period and probe sample size. This paper addresses the sampling issue of using probe vehicles for detecting traffic information. An extended Nyquist sampling theorem based on signal processing theory is proposed to derive bounds on...
Probe-vehicle technique is an effective method of collecting real-time traffic information on road networks. A technically feasible and cost-effective wireless communication network is in great demand so that large amounts of traffic data sampled by probe vehicles over a large geographical area can be sent to the traffic management center (TMC). However, how to design such a wireless network forms...
Using vehicles as probes is a flexible and low-cost way to obtain real-time traffic information. This paper addresses the sampling issues of using probe vehicles for detecting traffic information in a road network. A spatial and temporal analysis model based on signal processing theory is established and used to derive bounds on the sampling period, transmitting period and sample sizes of probe vehicles...
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