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Parkinson's disease (PD) is a neurodegenerative brain disorder that slowly brings on the dopaminergic neurons death. The depletion of the dopaminergic signal causes the onset of motor symptoms such as tremor, bradykinesia and rigidity. Usually, neurologists regularly monitor motor symptoms and motor fluctuations using the MDS-UPDRS part III clinical scale. Nevertheless, to have a more objective and...
Aim of this work is to design and develop an instrumented cylindrical object equipped with force sensors, which is able to assess grasping performance of both human and robotic hands. The object is made of two concentric shells between which sixteen piezoresistive sensors have been located in order to measure the forces applied by the hand fingers during grasping. Furthermore, a magneto-inertial unit...
Radiofrequency ablation (RFA) is a minimally invasive procedure used to treat tumors by means of hyperthermia, mostly through percutaneous approach. The tissue temperature plays a pivotal role in the achievement of the target volume heating, while sparing the surrounding healthy tissue from thermal damage. Several techniques for thermometry during RFA are investigated, most of them based on the use...
Nutritive Sucking (NS) is a highly organized process that can reflect infants' maturation during the early post-natal period. The assessment of NS may provide a sensitive means of evaluating early motor skills and their development. Thus, a reliable tool for assessing sucking behavior may benefit diagnostics and treatment of newborns since the first days of life. The aim of this work is to propose...
In newborns, a poor coordination between sucking, swallowing and breathing may undermine the effectiveness of oral feeding and signal immaturity of Central Nervous System. The aim of this work is to develop and validate a non-invasive device for recording respiratory events of newborns during bottle feeding. The proposed device working principle is based on the convective heat exchanged between two...
In this work we propose a new method to study the development of motor planning abilities in children and, in particular, in children at high risk for ASD. Although several modified motor signs have been found in children with ASD, no specific markers enabling the early assessment of risk have been found yet. In this work, we discuss the problem posed by objective and quantitative behavioral analysis...
Fiber Bragg Grating (FBG) technology is very attractive to develop sensors for the measurement of thermal and mechanical parameters in biological applications, particularly in presence of electromagnetic interferences. This work presents the design, working principle and experimental characterization of a force sensor based on two FBGs, with the feature of being compatible with Magnetic Resonance...
A bidirectional, low cost flowmeter for neonatal artificial ventilation, suitable for application in mono-patient breathing circuits, is described here. The sensing element consists of two nominally identical bipolar junction transistors employed as hot bodies. The sensor working principle is based on the convective heat transfer between the transistors, heated by Joule phenomenon, and the colder...
Motion capture based on magneto-inertial sensors is a technology enabling data collection in unstructured environments, allowing “out of the lab” motion analysis. This technology is a good candidate for motion analysis of children thanks to the reduced weight and size as well as the use of wireless communication that has improved its wearability and reduced its obtrusivity. A key issue in the application...
In this work, an alignment procedure of magneto-inertial units in the Special Orthogonal Space SO(3) is presented and discussed. The procedure, designed for ambulatory measurements of lower limb kinematic, is based on simple rotation movements around anatomical axes of hip joint and its accuracy is independent of the speed as well as the range of the movements. This is particularly important for movement...
This letter describes a novel approach to the assessment of spatial cognition in children. In particular, we present a wireless instrumented toy embedding magneto-inertial sensors for orientation tracking, specifically developed to assess the ability to insert objects into holes. To be used in naturalistic environments (e.g., day cares), we also describe an in-field calibration procedure based on...
This paper describes an interdisciplinary approach to the assessment on infants' behavior, with a focus on the technology. The goal is an objective, quantitative analysis of concurrent maturation of sensory, motor and cognitive abilities in young children, in relation to the achievement of developmental milestones. An instrumented block-box toy specifically developed to assess the ability to insert...
There are recent evidence which show how brain development is strictly linked to the action. Movements shape and are, in turn, shaped by cortical and sub-cortical areas. In particular spontaneous movements of newborn infants matter for developing the capability of generating voluntary skill movements. Therefore studying spontaneous infants' movements can be useful to understand the main developmental...
In this work, a novel technological approach to the early diagnosis of neuro-developmental disorders is presented. Disorders such as Autism are typically diagnosed after language development, i.e. after the 2–3 years of age. In this paper, three different typologies of instruments are presented which are designed to assess infants behavior in different perceptual and motor domains. The first is an...
In this work, a novel technological approach to the early diagnosis of neuro-developmental disorders is presented. Disorders such as Autism are typically diagnosed after language development, i.e. after the 2-3 years of age. In this paper, three different typologies of instruments are presented which are designed to assess infants behavior in different perceptual and motor domains. The first is an...
In this work, the kinematics of the human wrist during pointing tasks is assessed and discussed, especially in relation to the use of wrist robots. First, the existence of intrinsic kinematics constraints (or Donders' law, similarly to oculomotor system) for the human wrist during pointing tasks is verified. To this end, a novel approach based on a hand-held device is presented which allow assessing...
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