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An experimental measurement study involving surface profilometry and scanning electron microscopy (SEM) combined with MCNP4C-based Monte Carlo simulations was performed to evaluate anode surface roughness in aged X-ray tubes and to quantitatively predict its impact and relevance on generated diagnostic X-ray spectra. Surface profilometry determined that the center-line average roughness in the most...
The aim of this study is to investigate abnormalities in the brain tissue of patients with clinically isolated syndrome (CIS) suggestive of multiple sclerosis (MS). In this method, magnetization transfer ratio (MTR) parameter accompanied with segmentation regional measurements and histogram analysis were used to improve the evaluation of disease progression in CIS patients. Conventional MR imaging...
The aim of this study is to investigate abnormalities and characterize pathologic changes associated with demyelination in the brain tissue of patients with multiple sclerosis (MS). In this method, magnetization transfer parameters such as magnetization transfer ratio (MTR), magnetization transfer rate (Ksat) and native relaxation time of brain tissue with and without applying saturation pulse were...
Precise methods of modern radiation therapy such as intensity modulated radiotherapy (IMRT), brachytherapy (BT) and high LET irradiation allow for high dose localization in volumes of a few mm3. However, most dosimetry methods-ionization chambers, TLD arrangements or silicon detectors, for example-are not capable of detecting sub-mm dose variations or do not allow for simple dose imaging. Magnetic...
Today, by injecting iron oxide based nanoparticles (USPIO) as MRI contrast agents, it is possible to study lymphatic system and some specific tumors and their metastasis. The type of surface coating, and coating characteristics of the nanoparticles are important factors for the biological properties of nanoparticles and their destination target. On the other hand, these properties contribute to different...
A new method for fully automated segmentation of the colonic walls in volumetric CT data is proposed. Because each dataset requires long process time, this paper will focus on the development of an efficient segmentation method in half-sized volume data by an anatomical-oriented approach. The process utilizes global and local histograms of contrast enhanced fluids (CEF) to generate adaptive thresholds...
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