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The effect of imaging pulse sequences on the perfusion model of hyperpolarized tracers and its influence on the quantitative assessment of blood perfusion were simulated and studied. Using three different singular value decomposition (SVD) based regularizations, including truncated SVD and first and second order Tikhonov, perfusion related parameters were calculated and compared. The simulation results...
To investigate the feasibility of magnetic resonance imaging with laser-polarized 129 Xe we have undertaken the study of time dependences of the 129 Xe magnetization in the whole body and its build-up in the brain. We conclude that by increasing the production and absolute polarization of the 129 Xe, it will be possible to apply this technique...
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