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Dysregulation of Wingless and Int‐1 (Wnt) signaling has been strongly associated with development and progression of osteoarthritis (OA). Here, we set out to investigate the independent effects of either mechanical stress (MS) or inflammation on Wnt signaling in human neocartilage pellets, and to relate this Wnt signaling to OA pathophysiology. OA synovium‐conditioned media (OAS‐CM) was collected...
The environmental occurrence of long-chain mid-chain diols, keto-ols and mid-chain hydroxy fatty acids is reviewed. The published information is heavily biased towards organic-rich sediments, which strongly hampers interpretation. The composition of positional isomers of these compounds differs remarkably between cultures of microalgae from the genus Nannochloropsis, and sediments, suggesting that...
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