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Clinical studies have suggested a predisposing role of apolipoprotein E (apo E) and angiotensin converting enzyme (ACE) in the development of atherosclerosis and cardiovascular disease. The purpose of this study was to investigate the contribution of apo E allele and ACE I/D allele polymorphisms to the carotid intima-media thickness assessed by ultrasound. The study was carried out on 260 asymptomatic...
The apolipoprotein E (apo E) polymorphism plays an important role in determining interindividual differences in cholesterol levels. Little in known, however, about whether apo E allele polymorphism is associated with other cardiovascular risk factors. In this study we examined multiple cardiovascular risk factors in addition to lipoprotein serum levels by apo E genotype in 285 asymptomatic subjects...
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