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Deficits in processing spatial information have been observed in clinical populations who have abnormalities within the dopamine (DA) system. As psychostimulants such as methamphetamine (MA) are particularly neurotoxic to the dopaminergic system it was of interest to examine the performance of MA-dependent individuals on a task of spatial attention.51 MA-dependent subjects and 22 age-matched non-substance...
On the basis of our previous work studying regional cerebral glucose metabolism (rCMRglc) and Stroop interference in schizophrenic outpatients, we decided to test a few predictions in terms of the paranoid subtype's cerebral metabolism while performing, trial-by-trial, the Stroop color-word task. We predicted that the paranoid subtype patients would show left anterior temporal hypermetabolism and...
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