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Compared to controls, the lateral and medial tibial articular cartilage chondroitin sulfate (CS) content in male STR/Ort mice was elevated between 8 and 19 weeks of age, fell at 24–26 weeks and increased again thereafter. The CS cartilage content of CBA mice remained relatively unchanged.Cartilage CS content was measured in female CBA and STR/Ort mice and in male and female Balb C mice, all at 18...