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Cardiovascular disease (CVD) is a major cause of morbidity and mortality in developed countries. This study aimed to confirm the effect of common putative CVD-associated gene variants (FTO rs17817449, KIF6 rs20455, 9p21 rs10757274 and 2q36.3 rs2943634) on CVD manifestation, and determine whether this effect differs between younger (< 50years) and older CVD patients.1191 controls and 1889 MI patients...
This study aimed to determine whether there is a relationship between common FTO (rs17817449) and MC4R (rs17782313) gene variants and body mass reduction or weight loss after a one-month lifestyle intervention in overweight/obese children.We genotyped 357 unrelated non-diabetic Czech children (age 13.7±4.9years, average BMI at baseline 30.8±4.6kg/m 2 ). Biochemical and anthropometrical measurements...
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