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Background: Tumors of the pineal gland are relatively rare. Most are solid, infiltrative lesions characterized by either germ cell, glial, or pineal parenchymal origin. To our knowledge, none have been described that contain an admixture of both anaplastic glial and neuronal elements.Case report: The authors present a case of a primary anaplastic glio-neuronal tumor of the pineal gland in a 78-year-old...