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To estimate the effect of methyl group of dihydroguaiaretic acid, which shows many kinds of biological activities, on biological activity, both enantiomers of 9′-dehydroxyimperanene (5, 6) and 7,8-dihydro-9′-dehydroxyimperanene (7, 8) lacking one of the methyl groups of dihydroguaiaretic acid were synthesized. (S)-7,8-Dihydro-9′-dehydroxyimperanene (7) showed 4–6-fold higher cytotoxic activity than...
In snowy countries, heavy snow has a large influence on traffic flows. Snow on urban roads disturbs traveling of vehicles as a huge amount of snow is piled up on roadsides, which often obstructs smooth driving. In this paper, we propose a novel method to predict the speed of vehicles on each road segment in snowy cities. This estimation is helpful for urban traffic planning of local government or...
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