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The Wnt/β‐catenin pathway is implicated in the pathogenesis of hepatocellular cancer (HCC). We developed a transgenic mouse (TG) in the FVB strain that overexpresses Ser45‐mutated‐β‐catenin in hepatocytes to study the effects on liver regeneration and cancer. In the two independent TG lines adult mice show elevated β‐catenin at hepatocyte membrane with no increase in the Wnt pathway targets cyclin‐D1...
The complete sequence of the cDNA for the proα1(I) chain of mouse type I procollagen is presented. The encoded amino acid sequence shows 96% identity to the human proα1(I) collagen chain.
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