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The ethanolic extracts of the leaves and seeds of Bixa orellana showed a broad spectrum of antimicrobial activity. The activity of the leaf extract was more pronounced.
The ethanolic extracts of the leaves and flowering tops of Acanthospermum hispidum showed varying degrees of activity against a wide range of pathogenic bacteria. The activity resided mostly in the polar fractions of the alcoholic extract, being only slight in the non-polar fractions. No activity was observed for the aqueous extract of the fresh plant material.
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