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Formalin-fixed paraffin-embedded tissue (FFPET) samples are widely employed in Molecular Epidemiology and Forensic Genetics. However, the effects of formaldehyde on mitochondrial DNA (mtDNA) still remain unexplored. Our aim was to determine the presence of alterations in mtDNA caused by the process of fixation with formalin. FFPET, blood samples and fresh tissue samples were collected from autopsies...