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A group of α-lipoic acid N-phenylamides were synthesized employing a variety of amide coupling protocols utilizing electron deficient anilines. These compounds were then assessed for their ability to block androgen-stimulated proliferation of a human prostate cancer cell line, LNCaP. These structurally simple compounds displayed anti-proliferative activities at, typically, 5–20μM concentrations and...
The properties of the nickel(II)/2-hydroxy-5-nonylacetophenone oxime (HNAPO), an active ingredient in LIX 84, extraction system were characterised in a micellar system. The extinction coefficient, λ max of HNAPO (316nm) and the Ni 2+ complex (387nm) in a neutral micellar system, poly dispersed octa-ethyleneglycol mono-n-dodecyl ether (G 12 A 8 )...
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