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TIMP-1 has an important role in the regulation of extracellular matrix remodeling in many diverse reproductive processes, such as ovulation and implantation. In porcine follicles, secretion of TIMP-1 has been suggested to increase following gonadotropin surge (Smith et al. 1994, J. Anim. Sci. 72:1004-1012). Recent studies demonstrated that TIMP-1 is synthesized by porcine oviductal tissue throughout...