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To explore the major risk factors linking preoperative characteristics and anaesthesia-related death in dogs in referral hospitals in Japan.Observational cohort study.From April 1, 2010 to March 31, 2011, 4323 dogs anaesthetized in 18 referral hospitals in Japan.Questionnaire forms were collated anonymously. Death occurring within 48 hours after extubation was considered as an anaesthesia-related...