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A new sensing metric is proposed for a field-effect transistor (FET)-based biosensor. As proof of concept, a nanogap-embedded FET is studied to reduce data fluctuations that originate from process variations during FET fabrication and environmental variations stemming from bioexperiments. The new sensing metric utilizes a crucial gate voltage , which induces the maximum substrate...
This paper reports a novel electrical detection of label-free DNA by use of a MEMS electrostatic micro-switch. The electrostatic micro-switch detects the immobilization of probe oligonucleotides and their hybridization with target oligonucleotides using pull-in voltage shift in the micro-switch originated from negative charges of the oligonucleotides. A numerical simulation is analyzed to support...
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