Search results for: Yonghong Liao

Items from 1 to 12 out of 12 results

article

Optoacoustic analysis of the distribution of polymeric micelles in tumors

Zhaoqing Cong, Feifei Yang, Yun Zhao, Chunyu Liu, more

Journal of Controlled Release > 2017 > 259 > C > e188-e189

article

Preparation and evaluation of self-microemulsions for improved bioavailability of ginsenoside-Rh1 and Rh2

Feifei Yang, Jing Zhou, Xiao Hu, Stephanie Kyoungchun Yu, more

Drug Delivery and Translational Research > 2017 > 7 > 5 > 731-737

Due to intestinal cytochrome P450 (CYP450)-mediated metabolism and P-glycoprotein (P-gp) efflux, poor oral bioavailability hinders ginsenoside-Rh1 (Rh1) and ginsenoside-Rh2 (Rh2) from clinical application. In this study, Rh1 and Rh2 were incorporated into two self-microemulsions (SME-1 and SME-2) to improve oral bioavailability. SME-1 contained both CYP450 and P-gp inhibitory excipients while SME-2...

article

Metabolomic Analysis of Adipose Tissue in Rats Exposed to Triptolide

Chuanqin Hu, Yousheng Wang, Yonghong Liao, Jing Wang, more

Chromatographia > 2017 > 80 > 7 > 1079-1087

Triptolide is the main active component of Tripterygium wilfordii Hook. F., which is one of the forbidden species by the Chinese Ministry of Health. A GC–MS-based metabolomic approach was applied to estimate the adipose toxicity induced by triptolide. The metabolomic study discovered that triptolide exposure caused a remarkable increase in fatty acids. For instance, nonanoic acid, dodecanoic acid,...

article

Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease

Weiguo Peng, Thiyagarajan M. Achariyar, Baoman Li, Yonghong Liao, more

Neurobiology of Disease > 2016 > 93 > C > 215-225

Glymphatic transport, defined as cerebrospinal fluid (CSF) peri-arterial inflow into brain, and interstitial fluid (ISF) clearance, is reduced in the aging brain. However, it is unclear whether glymphatic transport affects the distribution of soluble Aβ in Alzheimer's disease (AD). In wild type mice, we show that Aβ40 (fluorescently labeled Aβ40 or unlabeled Aβ40), was distributed from CSF to brain,...

article

The effects of surface morphology on the aerosol performance of spray-dried particles within HFA 134a based metered dose formulations

Feifei Yang, Xiaobin Liu, Wei Wang, Chunyu Liu, more

Asian Journal of Pharmaceutical Sciences > 2015 > 10 > 6 > 513-519

The aim of this study was to produce fine particles with different corrugated degree of surface by spray-drying and to investigate the effect of surface morphology on in vitro aerosol performance of the particles within HFA 134a based metered dose formulations. Compositions of rizatriptan and scutellarin were spray-dried using different spray-drying parameters, and particles were suspended within...

article

Deletion of the znuA virulence factor attenuates Actinobacillus pleuropneumoniae and confers protection against homologous or heterologous strain challenge

Fangyan Yuan, Yonghong Liao, Wujin You, Zewen Liu, more

Veterinary Microbiology > 2014 > 174 > 3-4 > 531-539

The znuA gene is known to be important for growth and survival in Escherichia coli, Haemophilus spp., Neisseria gonorrhoeae, and Pasteurella multocida under low Zn²⁺ conditions. This gene is also present in Actinobacillus pleuropneumoniae serotype 1; therefore, the aim of this study was to investigate the existence of a similar role for the znuA gene in the growth and virulence of this organism. A...

article

Evaluation of a real-time RT-PCR assay using minor groove binding probe for specific detection of Chinese wild-type classical swine fever virus

Guoyuan Wen, Tao Zhang, Jun Yang, Qingping Luo, more

Journal of Virological Methods > 2011 > 176 > 1-2 > 96-102

A one-step real-time RT-PCR assay using a minor groove binding probe was developed for the specific detection of Chinese wild-type classical swine fever virus (CSFV). The assay detected wild-type CSFV strains representing different genotypes, but did not amplify viral RNA from the Hog Cholera Lipinized Virus (HCLV) vaccine-strain and other porcine viruses. The assay had a detection limit of 10copies/reaction...

chapter

Research of electronic audio and video management system based on PBAM

Zhiguo Meng, Yonghong Liao

2011 International Conference on Computer Science and Service System (CSSS) > 2444 - 2447

2011 International Conference on Computer Science and Service System (CSSS)

The electronic audio and video management system is a comprehensive information system of management science, information science, systems science and computer science. Under the environment of promoting service level and developing network operation, how to handle questions such as checking up account and cost accounting and so on, the research and development specialized electronic audio and video...

article

Anti-cancer effects of 20(S)-protopanoxadiol on human acute lymphoblastic leukemia cell lines Reh and RS4;11

Lihua Sun, Qiong Wang, Xinmin Liu, Nicolaas H. C. Brons, more

Medical Oncology > 2011 > 28 > 3 > 813-821

Although the treatment outcome of acute lymphoblastic leukemia (ALL) has been improved in the past decades by combination chemotherapy, toxic side-effects of chemotherapeutics remain a major problem. Therefore, new alternative agents with low toxicity are urgently needed. Natural products provide a rich source of screening potential anti-cancer drugs. 20(S)-protopanoxadiol (PPD), a major gastrointestinal...

article

Proteomics Analysis of Differential Expression of Chicken Brain Tissue Proteins in Response to the Neurovirulent H5N1 Avian Influenza Virus Infection

Wei Zou, Jianjiang Ke, Anding Zhang, Mingguang Zhou, more

Journal of Proteome Research > 2010 > 9 > 8 > 3789 - 3798

article

Brucein D induces apoptosis in pancreatic adenocarcinoma cell line PANC-1 through the activation of p38-mitogen activated protein kinase

Sin Ting Lau, Zhi-Xiu Lin, Yonghong Liao, Ming Zhao, more

Cancer Letters > 2009 > 281 > 1 > 42-52

Pancreatic cancer is a malignant disease with extremely high mortality. Our previous work found that Brucea javanica fruit possesses potent anti-pancreatic cancer activity. In the present study, brucein D (BD), a quassinoid found abundantly in B. javanica fruit, was evaluated for its anti-proliferative and apoptogenic actions. BD inhibited the growth of three pancreatic cancer cell lines, i.e., PANC-1,...

article

Overview on External Contamination Sources in Traditional Chinese Medicines

Jian Xue, Dongjing Liu, Shilin Chen, Yonghong Liao, more

World Science and Technology > 2008 > 10 > 1 > 91-96

External contamination sources (pesticide residues, heavy metals, solvent residues, and aflatoxin) and measurements and restriction standards that were published in previous studies, along with the authors' data were analyzed. It was found that the key to addressing the contamination is to place contamination source under control using mandatory standards.

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Search results for: Yonghong Liao

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