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Non‐genetic control over bacterial cellulose synthesis and the application for functional neuronal network formation is demonstrated in article number 1700331, by Byung Hee Hong, Myung‐Han Yoon, and co‐workers. Hybridization of bacterial cellulose with graphene oxide by dispersion of nanocarbon flakes in bacterial culture medium delicately modulates the resultant cellulose network properties and 3D...
Bacterial biopolymers have drawn much attention owing to their unconventional three‐dimensional structures and interesting functions, which are closely integrated with bacterial physiology. The nongenetic modulation of bacterial (Acetobacter xylinum) cellulose synthesis via nanocarbon hybridization, and its application to the emulation of layered neuronal tissue, is reported. The controlled dispersion...
Mesenchymal stem cells (MSCs) preferentially differentiate to osteogenic lineage when cultured on mechanically stiff substrates. However, collagen sponges, clinically approved scaffolds for bone regeneration, provide soft microenvironment to MSCs. Here, we demonstrate that the covalent conjugation of mechanically stiff graphene oxide (GO) flakes to three-dimensional (3D) collagen scaffolds improves...
The biomineralization of hydroxyapatite (HA) on silk nanofiber surface was explored to create organic/inorganic composite scaffold for bone tissue engineering. The porous silk nanofibers matrix was prepared by electrospinning using methanol coagulation bath as a collector and the deposition and coating of HA crystals were proceeded through biomineralization process by immersing the nanofibers in ten...
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