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It was hypothesized that white light can induce DNA single-strand breaks/alkali labile sites in lens epithelial cells during the dissection process when lenses are being collected for study. Dissection of lenses in white light significantly increased ‘Integrated Intensity’ (P=0.0216), an index of DNA single strand breaks/alkali labile sites, using the alkaline microgel electrophoresis assay. In addition,...
This study examined the effect of fluorescent light on the timing and severity of age-related cataracts in a fully pigmented mouse strain, the (C57BL/6×C3H)F1, that normally develops slowly progressing age-related cataracts only beyond middle age. Two groups of 56 animals each were exposed, respectively, either to a daily range of 66–222 foot candles (FC) or to 1FC of standard fluorescent lighting...
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